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• Diabetes, hyperglycaemia / metabolic syndrome / thrombocyte dysfunction, etc., Risk of cardiovascular complications
• Cardiovascular disease in diabetes occurs in the younger age, but is often present without symptoms.
• Low dosage aspirin proves first-class effects of cardiovascular disease in diabetics
Every November 14 is "World Diabetes Day". It is a day established by the International Federation for Diabetes (IDF) and the World Health Organization (VHO) to raise awareness of diabetes.
Diabetes mellitus is a metabolic disorder characterized by hyperglycaemia in which insulin is not well secreted or its normal function is not achieved, and blood glucose levels increase.
According to the Korean Diabetes Association, one in seven (14.4%) of adults over 30 are having diabetes in 2016. In addition, the level of diabetes control showed that only 6 out of 10 adults with diabetes were familiar with diabetes (awareness), half of those who received treatment (treatment rate), only one in 4 had diabetes Patient's glycemic index, glycemic target controls, is controlled at less than 6.5% (control rate).3
The reason for the treatment of diabetes is complication. Complications, and not diabetes, cause discomfort in everyday life or cause a decrease in life expectancy. Among the complications, cardiovascular disease is the leading cause of death in patients with diabetes. Monitor infectious diseases, malignant tumors and congestive heart failure.
* Among the deaths of six major hospitals in the city of Busan in the period 2000-2004, patients with type 2 diabetes older than 30 years
The risk factor for cardiovascular disease, the most dangerous complication, is 2-3 times higher in men with diabetes and 3-5 times higher in women than in people without diabetes.
Choi Dong-hoon, director of the Cardiovascular Hospital of Severance, said: "Diabetes patients have a higher risk of developing cardiovascular disease6 "Cardiovascular disease in patients with diabetes is more common in younger patients than in those without diabetes and is more frequent in patients with no symptoms. Because lesions are multiple and extensive, prevention and treatment of cardiovascular treatment is of the highest importance in diabetics."
Cardiovascular complications of diabetes, why?
There are different causes, but the following factors are typical.
First, it's hyperglycemia. It is known that high blood sugar levels increase the flow of blood vessels and promote atherosclerosis of the blood vessels themselves.
Second, hypertriglyceridemia and low levels of HDL cholesterol are increasing in patients with diabetes than in patients without diabetes who play an important role in the development of early atherosclerosis.
Third, hypertension. Hypertension is often accompanied by diabetes, which is a risk for atherosclerosis.
Finally, patients with diabetes have fibrinolysis, a platelet function, and so on, resulting in a coagulation phenomenon in which blood is well trapped. This can interfere with blood circulation and lead to cardiovascular complications.
Symptoms of cardiovascular complications related to diabetes7
Cardiovascular complications of diabetes may include neuropathic symptoms, macrovascular injuries, and microvascular injuries.
|
Symptoms associated with neuropathy |
• Diabetic neuropathy : Hand, Arm, Foot, With legs |
|
Large boat damage, |
• Pain in the chest, Difficulties in breathing : Myocardial infarction, Angina, Case of the heart • A headache, Dizziness, An abnormal excuse, Balance disorder : Stroke(Cerebral infarction)I have to doubt. • Back pain : Peripheral artery |
|
Capillary |
• reduced vision, Visual disorder : It can be associated with diabetic related retinopathy. • Reduced urine volume, Edema : It can be associated with a decreased kidney function. |
Three habits to prevent cardiovascular complications – Check the risk, Ask for advice, Take a low dose of aspirin,
[STEP1] Checking the risk of managing complications (checking)
To prevent diabetes, causing cardiovascular complications, it is necessary to consult a specialist and manage it through a checklist that can check the risk of cardiovascular diseases associated with common diabetes.
|
Risk
u For men 56Three, For women 66Being older than.
u Relatively early age(Male
u I'm smoking right now..
u Day 30Minute
u Obesity now too accumulated in the body(BMI(BMI) 30 Above)
u Total cholesterol(240 mg /Dl
u Have high blood pressure or diabetes. |
[ii]Guidelines for the treatment of dyslipidemia, 2015.
In addition, lifestyle changes need to be made healthier. Cigarettes must be cut off, alcohol should be reduced to one or two days, food should be balanced, eaten vegetables and fish. It should also be practiced more than 30 minutes a day to maintain proper weight and volume of the waist and reduce stress.
[STEP2] Low-dose aspirin, the first line treatment for cardiovascular disease in diabetics,
Consult a specialist to check the risk of cardiovascular disease, and then consider taking medicines such as low-dose aspirin. Low-dose aspirin is used to prevent cardiovascular disease by inhibiting thrombogenesis, by facilitating blood flow and by proving thrombogenic effects in patients with multiple cardiovascular risk factors. In a recent clinical trial of patients with diabetes without cardiovascular disease, the risk of serious vascular events was 12% lower than placebo and the dose of aspirin was 100 mg daily for 7,4 years. The study also found that a low dose of aspirin was effective in preventing primary cardiovascular events in patients with diabetes who had previously been thought to have less responsiveness to aspirin.
[STEP3] Cardiovascular preventive treatment with another appearance, stable hun-dose aspirin should retain habit (take)
If you are already taking low-dose aspirin for cardiovascular disease, it's important that you take it regularly. If you stop taking it for no apparent reason, the risk of cardiovascular disease may increase. It is important to regularly administer medication in accordance with a doctor's prescription, with diet management.
Choi Dong-hoon, chairman of the Department, said: "In today's cold weather, special attention should be paid to reduced blood sugar levels, increased blood sugar due to decreased exercise, overeating and overeating, diabetes may develop or worsen, blood vessels may contract the probability of cardiovascular the disease can grow. " "It is particularly necessary to manage two diseases so there is no misunderstanding that leads to cardiovascular disease disregarding diabetes management."
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References
2 National Health Insurance Corporation, know the disease that can get diabetes, 2013.
3 Korean Society for Diabetes, Diabetes Leaf in Korea 2018, 2018.
4 Park, KS, Change of the Ten Year Trend of Death in Type 2 Diabetes Patients, 2009
5 Korea Diabetes Association, Clinical Guideline 2013 [제3부]Diabetes and Complications, 2013
6 Center for Clinical Diabetes Study Type 2, Ministry of Health and Social Welfare, Guidelines for the Treatment of Cardiovascular Complications of Diabetes, 2007.
7 Ministry of Health and Social Welfare, Diabetes and Cardiovascular Diseases, Center for Cardiovascular Diseases, Chungbuk National University Hospital, 2018.
8 JNC Report 7, 2003.
9 Guidelines for the treatment of dyslipidemia, 2015
10 Nine Living Rules for the Prevention and Management of Cardiovascular Diseases, Ministry of Health and Social Welfare, 2011.
11 Raju N, et al. Effect of aspirin on mortality in primary prevention of cardiovascular diseases. Am J Med. 2011; 124: 621-9.
12 Collaboration of antitrombotic researchers (ATT). Aspirin in primary and secondary prevention of vascular disease: Collaborative meta-analysis of data from individual participants from randomized trials. Lancet 2007; 373: 1849-60.
13 Aspirin Protect your domestic production manual, 24/10/17.
14 Effects of aspirin for primary prevention in people with diabetes mellitus, Nev Engl J Med, 2018.
15, Park, Korea Drug alignment and cost burden by a medical group, Korea Institute of Health and Social Research, 2011.
16 Biondi-Zoccai et al., Eur Heart J 2006; 27: 2667-74.
17 Tetsuro, seasonal variations of severe hypoglycaemia in patients with type 1 diabetes mellitus, type 2 diabetes mellitus and non-diabetes mellitus, medicine. 2014; vol.
18 A.Analitis, Effects of cold weather on mortality: results of 15 European cities within the PHEVE project, American Journal of Epidemiology, 2008, vol.
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