Tuesday , March 28 2023

Coffee reduces the chances of Alzheimer's and Parkinson's disease


In addition to lighting our morning days and keeping us going all day, it has been shown that coffee has many health benefits: one suggests that caffeine content improves alertness and memory in the short term – but studies suggest that coffee may have long-term protective effects on the brain.

Drinking coffee was previously associated with a reduced risk of Alzheimer's and Parkinson's disease, and now scientists say they may have an idea as to why. It turns out that phenylindan – chemical compounds formed during the beer process – inhibit the growth of proteins associated with degenerative brain diseases. And the darker it is, the baking, say, more of these protective compounds is found in each glass.

For a new studio, published in Boundaries in neuroscience, researchers at the Kremlin Brain Institute in Toronto analyzed the chemical components of three different Starbucks samples of Instant Coffee: lightly baked, dark baked and decaffeinated dark baking. Then, they extracted an extract of each sample into two types of proteins – amyloid beta and tau – which are known to be Alzheimer's and Parkinson's disease. Studies have shown that as these conditions progress, these proteins tend to form clamps (known as amyloid plaques and tanglastic tanglastic proteins) in the brain.

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All three coffee extracts prevented the "accumulation" of these proteins, suggesting that something in American favorite morning beer could be protected from disease progression. And because the researchers did not notice any difference in the effectiveness of regular rice counterparts, they found that it was likely not caffeine that gives these advantages.

However, they observed greater inhibitory effects than two dark grills compared to baking. This has led researchers to think about phenylindanes – compounds formed from the decomposition of acids during baking of coffee, which are mainly responsible for the bitter taste of coffee.

Phenylindanes are found in higher concentrations in coffee with longer baking times, such as dark grill and espresso. They have been shown to exhibit "surprisingly strong antioxidant activity," they wrote in their article, but their ability to interact with amyloid and tau proteins has not been reported previously.

In further laboratory research, they found that the mixture of phenylindane really prevented the grouping of protein-related diseases; Actually, it was only a compound having an effect on amyloid and tau proteins was studied. For tau proteins, he showed stronger levels of inhibition than any other investigated unit.

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Since both extract of dark roasted coffee showed a stronger level of inhibition of protein versus light, the authors suggested that it was a phenylindanic component of coffee, which is largely responsible for this effect. (And good news for kids is asking: because the decafeinization process is happening Before the baking process, the authors assume that there is no effect on the phenylindane level.)

This does not necessarily mean that everyone should drink espresso or bake their extra dark grain, however. The research is still preliminary, says lead author Donald Veaver, MD, co-director of the Kremlin Institute of Brain and it is not yet known how these compounds really work in the human body. (In addition, other research suggests that easier baking has a higher level different useful compounds, so it can still be a throw for overall health.)

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Veaver said in a statement that he hopes this research will lead to further research into phenylindan, and perhaps to the development of drugs that could be used to treat neurodegenerative diseases. He also said that it is good to know that coffee has these naturally good good properties, even if there is not enough evidence to drink it for just that reason.

"What this study does is to take epidemiological evidence and try to improve it and to show that there are coffee components that are useful for the defense of cognitive decline," Veaver said. "It's interesting, but we suggest coffee is a cure? Absolutely not."

Experts say that the best way to protect your brain from aging is to monitor healthy eating, regular exercise and plenty of sleep. And if it turns out that Joe's day cup matches this plan, we're definitely all for it.

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